\n
\n\tNature dergisinde yay\u0131mlanan yeni bir ara\u015ft\u0131rma, hastanede yatan ve k\u00f6k h\u00fccre nakli \u00f6ncesinde uzun s\u00fcreli antibiyotik tedavisi g\u00f6ren kanser hastalar\u0131n\u0131n ba\u011f\u0131rsak bakterilerinde meydana gelen de\u011fi\u015fimleri inceledi.<\/p>\n
\n\tKanser tedavisi g\u00f6ren hastalar\u0131n yaln\u0131zca hastane taraf\u0131ndan haz\u0131rlanan g\u0131dalar\u0131 t\u00fcketmesi sayesinde ara\u015ft\u0131rmac\u0131lar hastalar\u0131n tam olarak ne kadar ve ne t\u00fcr besin ald\u0131\u011f\u0131n\u0131 takip edebildi. Ba\u011f\u0131rsak mikrobiyomunun sindirime yard\u0131mc\u0131 olma, vitamin \u00fcretme, ba\u011f\u0131\u015f\u0131kl\u0131k sistemini destekleme ve beyinle ileti\u015fim kurarak serotonin gibi n\u00f6rotransmiterlerin \u00fcretilmesinde rol oynama gibi kritik i\u015flevlere sahip oldu\u011fu biliniyor.<\/p>\n
\n\tHastanede yatan hastalar \u00fczerinde yap\u0131lan ara\u015ft\u0131rma<\/h2>\n
\n\tMemorial Sloan Kettering Kanser Merkezi, NYU Langone Health ve City of Hope Kanser Merkezi bilim insanlar\u0131 taraf\u0131ndan y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmada, 173 hastadan al\u0131nan 1.000’den fazla d\u0131\u015fk\u0131 \u00f6rne\u011fi ve t\u00fcketilen 9 bin 400’den fazla hastane \u00f6\u011f\u00fcn\u00fc incelendi.<\/p>\n
\n\tAra\u015ft\u0131rma ekibinden Dr. Jonathan Peled, ya\u011f, karbonhidrat ve lif gibi ana besin \u00f6geleri ile belirli g\u0131dalar\u0131n ba\u011f\u0131rsak bakterileri \u00fczerindeki etkilerini analiz ettiklerini belirtti.<\/p>\n
\n\tPeled, t\u00fcr\u00fc ne olursa olsun t\u00fcketilen \u015fekerli g\u0131dalar\u0131n, \u00f6zellikle de ilave \u015fekerlerin, antibiyotiklerle birle\u015fti\u011finde mikrobiyoma zarar verme konusunda g\u00fc\u00e7l\u00fc bir olumsuz etki yaratt\u0131\u011f\u0131n\u0131 ifade etti.<\/p>\n
\n\tZararl\u0131 bakterilerin \u00e7o\u011falmas\u0131na yol a\u00e7\u0131yor<\/h2>\n
\n\tHastalar\u0131n uygulad\u0131\u011f\u0131 antibiyotik rejiminin yo\u011funlu\u011fu artt\u0131k\u00e7a mikrobiyomlar\u0131ndaki \u00e7e\u015fitlilik kayb\u0131n\u0131n da b\u00fcy\u00fcd\u00fc\u011f\u00fc g\u00f6zlemlendi. Ara\u015ft\u0131rmada tatl\u0131, \u015fekerli g\u0131da ve i\u00e7ecek t\u00fcketimindeki her 100 graml\u0131k art\u0131\u015f\u0131n, antibiyotik tedavisi s\u00fcresince hastalar\u0131n d\u0131\u015fk\u0131 \u00f6rneklerindeki mikrobiyom \u00e7e\u015fitlili\u011fini yakla\u015f\u0131k y\u00fczde 24 oran\u0131nda azaltt\u0131\u011f\u0131 tespit edildi.<\/p>\n
\n\tBa\u011f\u0131rsak bakterilerindeki \u00e7e\u015fitlilik azalmas\u0131n\u0131n, “Enterococcus faecium” gibi baz\u0131 zararl\u0131 bakterilerin \u00e7o\u011falmas\u0131yla ba\u011flant\u0131l\u0131 oldu\u011fu kaydedildi. Normal \u015fartlarda ba\u011f\u0131rsakta zarars\u0131z bir \u015fekilde duran bu bakterinin, antibiyotiklerin di\u011fer faydal\u0131 bakterileri yok etmesiyle a\u015f\u0131r\u0131 \u00e7o\u011falabildi\u011fi, ba\u011f\u0131rsak duvar\u0131ndan kan dola\u015f\u0131m\u0131na s\u0131zarak sepsise veya organ reddi komplikasyonlar\u0131na yol a\u00e7abilece\u011fi aktar\u0131ld\u0131.<\/p>\n
\n\tFare deneyleri ve artan riskler<\/h2>\n
\n\tBilim insanlar\u0131 insanlarda g\u00f6zlemledikleri bu de\u011fi\u015fimi fareler \u00fczerinde de test etti. Geni\u015f spektrumlu tek bir antibiyotik i\u011fnesi yap\u0131lan farelere \u015feker verildi\u011finde, Enterococcus bakterisi miktar\u0131n\u0131n \u00fc\u00e7\u00fcnc\u00fc g\u00fcnde 16 kat, alt\u0131nc\u0131 g\u00fcnde ise 33 kat artt\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc.<\/p>\n
\n\tAra\u015ft\u0131rma verileri, ortalamadan daha fazla \u015feker t\u00fcketen hastalar\u0131n nakil sonras\u0131nda hayat\u0131n\u0131 kaybetme riskinin di\u011fer hastalara k\u0131yasla yakla\u015f\u0131k y\u00fczde 12 daha y\u00fcksek oldu\u011funu ortaya koydu. Enterococcus bakterisindeki a\u015f\u0131r\u0131 \u00e7o\u011falman\u0131n antibiyotik tedavisinden sonra yakla\u015f\u0131k sekiz g\u00fcn s\u00fcrd\u00fc\u011f\u00fc belirtildi.<\/p>\n
\n\tHouston’daki Baylor T\u0131p Kolejinden Dr. Anthony Maresso, \u00e7al\u0131\u015fman\u0131n hastanelerdeki beslenme programlar\u0131n\u0131n de\u011fi\u015ftirilmesi gereklili\u011fi konusunda \u00f6nemli soru i\u015faretleri do\u011furdu\u011funu ifade etti.<\/p>\n
\n\tDr. Peled ise elde edilen bulgular\u0131n, ki\u015filerin t\u00fcm hayatlar\u0131 boyunca de\u011fil, \u00f6zellikle antibiyotik kulland\u0131klar\u0131 d\u00f6nemlerde \u015feker t\u00fcketimini s\u0131n\u0131rland\u0131rmalar\u0131n\u0131n faydal\u0131 olabilece\u011fini g\u00f6sterdi\u011fini vurgulad\u0131.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
Nature dergisinde yay\u0131mlanan yeni bir ara\u015ft\u0131rma, hastanede yatan ve k\u00f6k h\u00fccre nakli \u00f6ncesinde uzun s\u00fcreli antibiyotik tedavisi g\u00f6ren kanser hastalar\u0131n\u0131n ba\u011f\u0131rsak bakterilerinde meydana gelen de\u011fi\u015fimleri inceledi.
Kanser tedavisi g\u00f6ren hastalar\u0131n yaln\u0131zca hastane taraf\u0131ndan haz\u0131rlanan g\u0131dalar\u0131 t\u00fcketmesi sayesinde ara\u015ft\u0131rmac\u0131lar hastalar\u0131n tam olarak ne kadar ve ne t\u00fcr besin ald\u0131\u011f\u0131n\u0131 takip edebildi. Ba\u011f\u0131rsak mikrobiyomunun sindirime […]<\/p>\n","protected":false},"author":1,"featured_media":49970,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_social_meta":[],"jnews_override_counter":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-49969","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\n
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Haber Ver K\u0131br\u0131s","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/haberverkibris.com\/index.php\/2026\/10\/03\/antibiyotik-kullanimi-sirasinda-seker-tuketmek-bagirsak-bakterilerine-zarar-verebilir\/","og_locale":"tr_TR","og_type":"article","og_title":"Antibiyotik kullan\u0131m\u0131 s\u0131ras\u0131nda \u015feker t\u00fcketmek ba\u011f\u0131rsak bakterilerine zarar verebilir - Haber Ver K\u0131br\u0131s","og_description":"
Nature dergisinde yay\u0131mlanan yeni bir ara\u015ft\u0131rma, hastanede yatan ve k\u00f6k h\u00fccre nakli \u00f6ncesinde uzun s\u00fcreli antibiyotik tedavisi g\u00f6ren kanser hastalar\u0131n\u0131n ba\u011f\u0131rsak bakterilerinde meydana gelen de\u011fi\u015fimleri inceledi.
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